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Big Anti-Aging Hit
Hydrogen’s size allows cell transformations responsible for longevity, performance enhancement and even weight loss without dieting.
Because of its size, molecular hydrogen can do a lot of things larger molecules of known antioxidants can’t. Molecular hydrogen affects all cells of the body, crosses the blood-brain barrier and can move readily into the cell energy factories (mitochondria); it “even has the ability to translocate to the nucleus under certain conditions,” reports Dr Brandon J Dixon in Medical Gas Research.
Once in these ideal locations of the cell, molecular hydrogen’s effects are documented as being an antioxidant, anti-inflammatory and influencing the genetics of cell life.
Studies conducted since 2007 find molecular hydrogen’s use in health could change the physiological fate of at least 183.6 million Americans—and what’s more its effects can be obtained with a dietary supplement.
Studies show people with diabetes, arthritis, heart disease and high cholesterol who consume extra amounts of molecular hydrogen experience lower blood sugar, inflammation, cholesterol and higher antioxidant activity. Molecular hydrogen could also find its place in sports performance, age-related dementia and Parkinson’s disease.
How this one molecule affects so many different systems and organs is a question researchers have been examining ever since the seminal molecular hydrogen in health medicine article came out in Nature Medicine in 2007.
More than 400 scientific studies, including 30-plus human clinical evaluations, most conducted in the last seven years, find molecular hydrogen effective in seemingly every organ of the body and in 140 human disease models, says the Molecular Hydrogen Research Foundation.
Aging Diseases and Hydrogen
The human studies have focused, in particular, on diabetics. These participants went into their trials with high blood sugar, blood pressure, cholesterol levels, inflammation, obesity and insulin resistance, all hallmarks of aging diseases. Known as Syndrome X or metabolic disease, one in three adults in the US experience these symptoms.
In 2008 researchers looked at the effect of supplementing molecular hydrogen in diabetics and others with poor sugar control. The main cause of aging among diabetics especially is oxidative stress, caused by free radicals whose elevated production is linked with pre-disease states.
The study investigated the effects of H2 intake on cholesterol and sugar levels in 30 patients with either type 2 diabetes mellitus (T2DM) or impaired glucose tolerance (IGT). The patients consumed either pressurized hydrogen-rich pure water or 900 mL of placebo pure water for 8 weeks with a 12-week washout period. Patients in the hydrogen water group experienced “decreases in the levels of modified low- density lipoprotein (LDL) cholesterol... small dense LDL and urinary 8-isoprostanes.”
Cholesterol and Weight Loss
Hydrogen intake decreased serum concentrations of oxidized LDLs, the kind of cholesterol linked with artery and heart disease. Levels of the fat-burning hormone adiponectin (that aids weight loss) and superoxide dismutase (SOD), one of the body’s primary antioxidants, went up.
In 4 of 6 patients with IGT, hydrogen “normalized” oral glucose tolerance tests.
Long-term intake of hydrogen “controlled fat and body weights despite no change in the consumption of food and water” and decreased blood sugar, insulin and triglycerides, the effect of which was similar to diet restriction, according to an independently confirming study. Gene expression in the liver was enhanced and expressed as the protein-based fibroblast growth factor 21 “which should function to enhance fatty acid and glucose expenditure. These results suggest the potential benefit of H2 in treating obesity, diabetes and metabolic syndrome.”
The difficulty of delivering hydrogen- enriched water is that it can only hold about 1.6 ppm of H2 unless pressurized. However H2 can also be produced via a dietary supplement and delivered to the tissues through the interaction of specific types of magnesium, malic acid and hydrogen bound in water. A molecular hydrogen dietary supplement can be taken daily. One supplement delivers three types
of magnesium with micro-encapsulated malic and fumaric acids and 74 bio- available coral minerals. As the capsule ingredients react, millions of tiny H2 bubbles saturate the body’s cells to raise mitochondrial (energy) and antioxidant activity, especially SOD and glutathione, as well as positively influence cell signalling and gene expression. These anti-aging effects may increase one’s overall state of health, say anti-aging physicians such as Julian Whitaker, MD who’s begun to recommend molecular hydrogen to patients as a daily supplement.
Abrous DN, Koehl M, Le Moal M. Adult neurogenesis: from precursors to network and physiology. Physiol Rev. 2005;85:523– 569. [PubMed]
Aoki K, Nakao A, Adachi T, Matsui Y, Miyakawa S. Pilot study: effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes. Med Gas Res. 2012 Jul 12;2:12. doi: 10.1186/2045-9912-2-12. ecollection 2012.
Dixon BJ, Tang J, Zhang JH. The evolution of molecular hydrogen: a noteworthy potential therapy with clinical significance. Med Gas Res. 2013; 3: 10. Published online 2013 May 16. doi: 10.1186/2045-9912-3-10PMcID: PMc3660246
Fujita K, Seike T, Yutsudo N, et al. Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease. PLoS One. 2009;4:e7247. [PMc free article][PubMed]
Fu Y, Ito M, Fujita Y, et al. Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson’s disease. Neurosci Lett. 2009;453:81–55. [PubMed]
Ishibashi T, Sato B, Rikitake M, Seo T, Kurokawa R, Hara Y, Naritomi Y, Hara H, Nagao T. consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study. Med Gas Res. 2012 Oct 2;2(1):27. doi: 10.1186/2045-9912-2-27.
Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, Kitawaki J, Imai S, Nakano K, Ohta M, Adachi T, Obayashi H, Yoshikawa T. Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res. 2008 Mar;28(3):137-43. doi: 10.1016/j.nutres.2008.01.008. Kamimura N, Nishimaki K, Ohsawa I, Ohta S. Molecular Hydrogen Improves Obesity and Diabetes by Inducing Hepatic FGF21 and Stimulating energy Metabolism in db/db Mice. Obesity (Silver Spring) 2011 in press. [PubMed]
Nagata K, Nakashima-Kamimura N, Mikami T, Ohsawa I, Ohta S. consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in mice. Prog Neuropsychopharmacol. 2009;34:501–508. [PubMed]
Nakao A, Toyoda Y, Sharma P, evans M, Guthrie N. effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. J clin Biochem Nutr. 2010 Mar;46(2):140-149. doi: 10.3164/jcbn.09-100. e-pub 2010 Feb 24.
Oharazawa H, Igarashi T, Yokota T, et al. Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen- loaded eye drops in retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci. 2010;51:487–492.
Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 2007, 13:688-694. PubMed Abstract | Publisher Full Text
6 Uses of Molecular Hydrogen
Hydrogen is hundreds of times smaller than other antioxidants like our old friends vitamin C and glutathione.
Antioxidants fight oxidation inside and out, keep people younger and prevent premature tissue aging and death. As it turns out molecular hydrogen, because of its ease of access to interact with every area of the cell, is an effective antioxidant. A study examined the antioxidant potential of molecular hydrogen in an open label, 8-week study on 20 subjects with pre-diabetes symptoms. The consumption of molecular hydrogen for 8 weeks resulted in a 39% increase in antioxidant enzyme superoxide dismutase (SOD). Further, subjects demonstrated an 8% increase in high density lipoprotein (HDL)-cholesterol and a 13% decrease in total cholesterol/HDL-cholesterol from baseline to week 4.
Molecular hydrogen was studied for its ameliorating influence on rheumatoid arthritis (RA), a chronic inflammatory disease. Twenty patients received 4 to 5 parts per million molecular hydrogen every day for 4 weeks. All the 5 patients with early RA who did not show antibodies “achieved remission, and 4 of them became symptom-free at the end of the study. The symptoms of RA were significantly improved...”
3. Cognitive Decline
Additional experimental studies demonstrate hydrogen prevents brain rust that leads to dementia. “Continuous consumption of hydrogen reduced oxidative stress in the brain and prevented the stress-induced decline in learning and memory.”
In Parkinson’s disease, mitochondrial dysfunction and oxidative stress are causes of cell loss in the area of the brain called the substantia nigra. H2 was given in an experimental model of Parkinson’s disease and “prevented both the development and progression of nigrostriatal degeneration” and “likely retards the development and progression of Parkinson’s disease.”
5. Muscle Fatigue
Muscle contraction during short intervals of intense exercise causes oxidative stress, which can develop overtraining symptoms including increased fatigue, muscle injury and inflammation. Ten male soccer players, average age 20, were subjected to exercise tests and blood sampling. Intake of molecular hydrogen prevented an elevation of blood lactate during heavy exercise. Peak torque significantly decreased in the control group in the early phase, suggesting muscle fatigue, but didn’t among the molecular hydrogen water group. This means more endurance in the hydrogen group.
H2-loaded eye drops were prepared by dissolving H2 in saline and directly administering to the ocular surface. The direct application of eye drops containing H2 ameliorated pressure and oxidation.
Spice Up Winter
For Super Immunity
PHOTOGRAPHY BY MIEKO HORIKOSHI
Cold weather is the time when building immunity becomes a matter of survival. Since certain types of foods provide our best immune building power, let’s enjoy summery flavor while giving our bodies the spices and peptides it needs. In this month’s recipes, you will see a common theme of foods like onions, garlic, ginger, turmeric, rosemary and also some powerful immune-building supplements. And, since we all love sweets there is also a way to give our bodies a big boost while pumping up the protein and essential fatty acids. Go for it, so you can sail through the winter and be ready to cruise into spring.
Chef Susan Teton’s online courses at www.chefTeton.com supply recipes for raw, cooked and cultured foods.
High Protein Black Bean Fudge
- 2 C black beans (if canned, drain)
- 3/4 C cocoa powder
- 6T Barlean’s Coconut Oil
- 1-2 scoops MHP Chocolate Flavored Protein
- 6T Lite&Sweet soaked in about 1/3 cup of water
- 1t vanilla extract
- 4t chocolate chips
- 1⁄2 C walnuts (chopped)
- 1⁄2t salt
- 1⁄2 t each of cinnamon and cayenne
Optional Supplements: Immune-Tree Colostrum6 and up to 1 tsp of Coral EcoPure.
Optional Sweeteners: sugar, honey or maple syrup.
In a food processor blend all of the ingredients, except walnuts, until smooth. Place mixture into a spring form pan or glass dish. Line with wax paper so it will be easier to remove in one piece. Press walnuts into the top of the mixture and refrigerate. Remove when it is firm and and cut into desired pieces. Keep refrigerated.
Drink away heart disease risk with juices from the local grocery led to improvements in cranberry juice cocktail’s polyphenols whose effects on blood flow, arterial stiffness and blood pressure are apparent within 24 hours, says Dr ana Rodriguez- Mateos, a cardiology professor at the University of Düsseldorf in Germany, at the 2015 Cranberry Health Research Conference.
Ten healthy men between ages 18 to 40 drank two cups of sweetened cranberry juice a day. their blood flow, arteries and blood pressure were measured over 24 hours. even cocktail cranberry all aspects of circulatory fitness.
“Cranberry juice is a rich source of phytonutrients,” says Rodriguez-Mateos. Due to this “robust” profile of polyphenols, the team sought to evaluate the immediate vascular impact.“Significant improvements in vascular function from drinking two cups of cranberry juice suggest an important role for cranberries in a heart-healthy diet.”
More good news for the holiday season: cranberry sauce has been found to protect from infections, inflammation and lower heart disease risk.
Fig Hemp macaroon Bars
- 2C shredded coconut
- 1⁄2C almond meal flour
- 1⁄2C hulled hemp seed hearts
- 1⁄2C coconut oil
- 1/3 C water
- 1/4 C dried figs (cut into small pieces)
- 4-5 T Lite&Sweet
- 1 T fresh ginger
- 1 T vanilla
- salt to taste
- sweeten with Lite Sweet to taste
Optional Supplements: Immune-Tree Colostrum6 and up to 1 tsp Coral EcoPure
Cut figs and soak in the 1/3 cup water. Add the vanilla and Lite&Sweet to the water mixture so that it can dissolve. Grate ginger. Mix coconut oil, ginger and wet mixture. Add into dry ingredients and salt to taste. Prepare for refrigeration by lining the container with wax paper or plastic wrap with edges hanging over the side of the dish (this makes for easy removal of contents). Press mixture into the dish and refrigerate. When firm, remove and cut into pieces. Keep refrigerated.
- 1-2 Dr. Praeger’s Super Greens Veggie Burgers
- 1 onion—thinly sliced
- 3-4 cloves of garlic chopped
- 1T Barlean’s Coconut Oil
- 1-2 T olive oil
Steamed veggies of choice (shown here are cauliflower, broccoli and carrots). What makes this recipe delicious is the flavor of Dr. Praeger’s Super Greens Veggie Burgers. They have a veggie flavor with spices (black pepper, cayenne pepper, coriander) to enliven any dish. Since everyone always asks me, “What do I do with vegetables?” here is an answer. And it is so simple. Place coconut oil in a skillet until it is hot. Add in onions and garlic and sauté until onions are close to caramelizing. Move them to the side of the pan and place the patties in the skillet and cook along with the onions while they caramelize. In a saucepan steam veggies of choice until desired tenderness. When the burger patties are thoroughly cooked, add them to the onion mixture and top onto the steamed veggies. Add other veggies and/or tomatoes as desired. Top with fresh olive oil, and salt and pepper.
Dried plums feed good bacteria by doing so they may reduce the risk of colon in your gut, says a study from texas a&M University in College Station, and the University of North Carolina at Chapel Hill, funded by the California Dried Plum Board and presented at the 2015 experimental Biology Conference in Boston. these good bacteria reduce colon cancer risk too, according to the study.
“Through our research, we were able to show that dried plums promote retention of beneficial bacteria throughout the colon andcancer,” Dr. Nancy Turner, Texas A&M AgriLife research professor in the nutrition and food science department, said.
The intestinal contents and tissues that were examined had significantly reduced numbers of aberrant crypts, aberrant crypt foci and high-multiplicity aberrant crypt foci, meaning lower cancer risk. these aberrant crypt foci are one of the earliest observable precancerous lesions and are often considered to be a strong indicator for cancer development.
Creamy Miso Soup
- 2C water
- 1 onion (rough chopped)
- 4 cloves garlic (roughchopped)
- 1 in+ piece of fresh turmeric
- 1 in+ piece of fresh ginger
- 1 sprig rosemary
- 2T miso of choice
- 2T Immune-Tree Colostrum6
Mince rosemary leaves. Place all ingredients together in a saucepan and cook (the slower the better) on low to medium heat until food contents are soft. When veggies are soft, place entire contents of pan into the blender. Add miso and ImmuneTree Colostrum6 and blend until creamy. Yum!
Sweet Berry Salad
- 1⁄2 C plain yogurt
- 1⁄2 cucumber
- 1 T balsamic vinegar
- 1 T Immune-Tree Colostrum6
- 2 T Barlean’s Swirl (Blackberry or
- 2 T Pomegranate Blueberry)
- 1⁄2 T Coral EcoPure
- salt and pepper to taste
Place all ingredients in a blender and blend until smooth. Salt and pepper to taste. Top salad greens with berries and walnuts.
Vibrant Cottage Cheese Salad
- 1 C organic cottage cheese (whole milk is best)
- 1 scoop NovaForme PhytoPro—Vanilla Flavored Organic Protein
- 2 T fresh lemon juice
- 1 T finely grated ginger
- 1 T Immune-Tree Colostrum6
- 1/4 T Coral EcoPure
Mix all ingredients together. Add toppings of choice: grapes, bananas, walnuts, apples or berries.